Neurosciences bordeaux
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  Researcher:
 
  Benjamin Dehay
Researcher PhD
INSERM
inserm
  Researcher
Address:
Institut des maladies neurodégénératives
CNRS UMR 5293
Université de Bordeaux
Bât 3B 1er étage
146 rue Léo Saignat

33076 Bordeaux cedex
Phone: +33 05 57 57 16 85
Fax: +33 05 56 90 14 21

Mail du chercheur: mail
tel: 33 (0)5 57 57 16 85
  Team:
Pathophysiology of parkinson's syndrome - Erwan Bezard  
 
  Program areas:
Normal and pathological motor control

FENS Themes:
Neurological and psychiatric conditions / Neurodegenerative disorders ; Neurological and psychiatric conditions / Aging

Scientific expertise:
apoptosis ; Cellular and molecular biology ; Parkinson's disease ; degenerative disease ; animal models of Parkinson's disease ; mTOR (mammalian target of rapamycin) ; neural degeneration ; development

Technical expertise:
image analysis ; biochemistry ; cellular biology ; molecular biology ; cellular and organotypic culture ; immunocytochemistry ; culture and transfection of neurons ; culture and transfection of neurons

Keywords:
alpha-synuclein ; apoptosis ; basal ganglia ; Cellular and molecular imaging ; Huntington' disease ; cellular neurobiology ; neural degeneration ; neurodegenerative and neurodevelopmental disorders ; Parkinson's disease ; aging
   
   
 
Research interests: I studied Biology at the University of Paris XI – Orsay (France). I got my Master at the University Paris XI and my Ph.D. at the University of Paris VI (CNRS ENS UMR 8541, Paris, France), working under the supervision of Dr. Anne Bertolotti on the identification of polyQ aggregation modulators in yeast and mammalian models of Huntington’s disease. To complete my formation with a more in-depth study of molecular mechanisms of neuronal cell death and expand my skills to in vivo approaches, I joined the laboratory of Dr. Miquel Vila at the Vall d’Hebron Research Institute (Barcelona, Spain) in February 2007 as a post-doctoral investigator. I participated in the unraveling of the role of different BH3-only molecules in experimental models of Parkinson’s disease by applying genetic and pharmacological interventions. Subsequently, I developed a research project to understand the mechanism and significance of Lewy Body formation in PD. In particular, we assessed the potential implication of alterations in autophagy-lysosomal degradation pathways in PD-related neurodegeneration and inclusion formation. I joined the group of Dr. Erwan Bezard in January 2010.
Publications: Clic here
   
   
     
 
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