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Daniel Choquet
Researcher - PhD
CNRS |
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Researcher
Team leader
Technological platform leader
Platform Bordeaux Imaging Center |
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Address:
CNRS UMR 5091 PCS
Institut François Magendie
146 rue Léo Saignat
33077 Bordeaux cédex
Phone: Tel 05 57 57 40 80
Fax: Fax 05 57 57 40 82
Mail du chercheur: 
tel: 0557574090 |
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Program areas:
Synapse
FENS Themes:
Development / Synaptogenesis and activity-dependent development ; Synaptic transmission and excitability ; Synaptic transmission and excitability / Cytoskeleton ; Synaptic transmission and excitability / synaptic maturation ; Synaptic transmission and excitability / Neurotransmitters ; Synaptic transmission and excitability / Synaptic plasticity ; Synaptic transmission and excitability / extracellular matrix proteins ; Synaptic transmission and excitability / Ligand gated ion channels ; Synaptic transmission and excitability / Synaptic transmission ; Synaptic transmission and excitability / Intracellular signalling pathways ; Synaptic transmission and excitability / Intrinsic membrane properties
Scientific expertise:
cellular biology ; synapse ; synaptogenesis ; nano-photonic ; receptor trafficking ; synaptic plasticity ; adhesion proteins
Technical expertise:
photonic imaging ; cellular and organotypic culture ; real time dynamic of membrane receptors ; patch-clamp electrophysiology ; calcium imaging ; immunohistochemistry ; light microscopy ; confocal microscopy
Keywords:
synapse ; glutamate receptor ; receptor trafficking ; synaptic plasticity ; opto-photonic ; single molecule imaging ; multiphoton imaging
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| Research projects: |
The objective of our group is to understand the dynamics of the processes involved during the formation and plasticity of glutamatergic synapses in the central nervous system. For this aim, we combine high resolution imaging, nano-manipulation, neurophysiology and cell biology approaches.
Main projects
Development of high resolution imaging techniques in living cells and tissues
Single molecule imaging to track receptors movements in and out synapses
Multiphoton and FRET imaging
Dynamic of glutamate receptor organization
Regulation of AMPA and NMDA receptor mobility in and out synapses by neuronal activity
Regulation of glutamate receptor mobility by scaffolding proteins
Dynamic of lipid organization in synapses
Roles of adhesion proteins in synaptogenesis
Dynamics of adhesion protein-cytoskeleton interactions
Role of mechanical constraints in synapse organization
Role of adhesion proteins in glutamate receptor organization. |
| Team: |
Dynamic imaging of membrane protein organization - Daniel Choquet |
| Publications: |
Clic here |
| More information: |
Cliquer ici |
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