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Bernard Bioulac
Professor - Hospital practitioner - MD-PhD
CHU Pellegrin Bordeaux ; CNRS ; Université Bordeaux 2 |
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Researcher
Director - Bordeaux Neuroscience Institute IFR 8
Hospital practitioner- Service d'Explorations fonctionnelles du système nerveux, Pôle Neurosciences cliniques - CHU Bordeaux Hôpital Haut-Lévêque
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Address:
CNRS UMR 5227 MAC
Mouvement - Adaptation - Cognition
Université Victor Segalen Bordeaux 2
Bât. 3A- 3ème étage-Case 22
146 rue Léo Saignat
33076 Bordeaux cedex
Phone: +33 05 57 57 15 85
Fax: +33 05 56 90 14 21
Mail du chercheur: 
tel: +33 05 57 57 15 49 |
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Program areas:
Normal and pathological motor control
Synapse
FENS Themes:
Motor systems / Basal ganglia ; Synaptic transmission and excitability / Synaptic transmission ; Synaptic transmission and excitability / Intrinsic membrane properties ; Neurological and psychiatric conditions / Neurodegenerative disorders
Scientific expertise:
pathophysiology of basal ganglia ; subcortical nucleus ; Parkinson's disease ; animal models of Parkinson's disease ; movement disorders
Technical expertise:
patch-clamp electrophysiology ; immunohistochemistry ; molecular pharmacology ; deep brain stimulation ; high-frequency stimulation
Keywords:
dopamine ; electrophysiology ; basal ganglia ; Parkinson's disease ; synaptic plasticity ; GABA receptor ; synaptic transmission ; high-frequency stimulation
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| Research interests: |
Our research activity focuses on the functioning of the basal ganglia networks and principally a group of the subcortical nucleus. This group is involved in the control of the voluntary movement and the principal Parkinson’s disease dysfunction.
Our research project aims to understand :
- the synaptic and molecular mechanisms leading the physiological and pathophysiologic activities in basal ganglia networks
- the high-frequency stimulation mechanisms leading to the benefic effects for the Parkinson patients.
Our approach integrates different approaches from the subcellular level to the exam in networks activity in vitro .
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| Team: |
Dynamic and pathological basal ganglia - Christian Gross |
| Publications: |
Clic here |
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